Objective: To observe the serum aminotransferase changes of patients with fatty liver changes after surgery and diagnosis value of transaminase level in the fatty liver.Methods: The serum aminotransferase were detected before treatment and after treatment 1,3,1 days in 60 patients with fatty liver liver resection, and recorded the patients' hepatic inflow occlusion, blood loss, surgical time and operation way.Results: The postoperative serum transaminase levelswere significantly higher than preoperative (P＜0.05 or P＜0.01), its increased on day 1 peak and then decreases to close to 7 days (P＞0.05).In the impact of ALT, AST change factors, the intraoperative hepatic inflow occlusion, surgical methods were the main factors for the result of serum transaminase elevation (P＜0.05), and after a linear relationship with serum transaminase increased.Conclusion: The detection of postoperative serum transaminase, can effectively prevent postoperative liver dysfunction, standardize the surgical procedure to provide a scientific basis.%目的:观察脂肪肝患者术后血清转氨酶的变化规律,转氨酶水平检验在脂肪肝诊断中的应用价值.方法:检测60例肝切除术脂肪肝患者治疗前与治疗后第1、3、7天血清转氨酶,并记录患者的入肝血流阻断、术中出血量、手术时间和手术方式等.结果:脂肪肝患者术后第1、3、7天血清转氨酶水平较术前均有显著升高(P<0.05或P<0.01),术后第1天到达峰值(P<0.01),然后逐渐降低,术后第7天比较接近术前水平(P>0.05).在影响ALT、AST发生变化的因素方面,术中入肝血流阻断、手术方式是导致术后血清转氨酶升高的主要因素(P<0.05),与术后血清转氨酶增高呈线性关系.结论:对手术后血清转氨酶的检测,可以有效防治术后肝功能异常,为规范手术操作提供科学的依据.
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