目的：探讨立止血与垂体后叶素联合应用治疗肺结核咳血的临床效果。方法选取2011年3月～2014年9月我院内科保守治疗的50例肺结核咳血患者做为研究对象。按照入院顺序随机分为实验组25例与对照组25例，对照组患者给予抗结核治疗和静脉滴注垂体后叶素治疗，实验组在抗结核治疗和持续静脉微泵推注垂体后叶素基础上联合立止血治疗。对比两组患者的疗效与不良反应出现情况。结果实验组患者的治疗效果好于对照组者，差异具统计学意义（P ＜0.05）。实验组患者平均止血时间少于对照组患者，差异有统计学意义（P ＜0.05）。N 端脑钠肽及 CK-MB、CK 指标两组间差异无统计学意义（P ＞0.05）。实验组患者不良反应发生情况少于对照组，差异有统计学意义（P ＜0.05）。结论临床应用立止血与垂体后叶素治疗肺结核咳血患者，治疗效果显著，联合用药后止血更快，减少患者出血时间，副作用较小，值得广泛推广应用。%Objective To investigate the clinical effect of reptilase combined with pituitrin used in the treatment of pulmonary tuberculosis hemoptysis. Methods 50 cases of pulmonary tuberculosis hemoptysis patients from 2011 March to 2014 September in our hospital of internal department with conservative treatment were selected as the study object.According to the order of admission they were randomly divided into experimental group 25 cases and control group 25 cases,control group patients were given anti tuberculosis therapy and intravenous injection of Pituitrin in the treatment,the experimental group in anti tuberculosis therapy and intravenous micro pump infusion pituitrin basis and reptilase in treatment.Comparison of curative effect of two groups with adverse reactions were made. Results Patients in the experimental group treatment effect was better than the control group,the difference has statistical significance(P < 0.05).Patients in the experimental group average hemostasis time was less than patients in the control group,and the difference has statistical significance(P < 0.05).N terminal brain natriuretic peptide and CK-MB,differences between the two groups in the CK index had no statistical significance(P > 0.05).The occurrence of adverse reactions of patients in the experimental group than in control group,the difference has statistical significance (P < 0.05). Conclusion Clinical application of reptilase and pituitrin in the treatment of pulmonary tuberculosis hemoptysis patients,the treatment effect is significant,combination of hemostatic faster,reducing the time of bleeding, less side effect,it is worth popularizing widely application.
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