Objective To explore the clinical efficacy of Compound Glycyrrhizin Tablets combined with levocetirizine hydrochloride in the treatment of neurodermatitis. Methods 86 cases of neurodermatitis patients were randomly divided into the treatment group and the control group, both of which were given treatment of mizolastine and clobetasol propionate cream. The treatment group was additionally given Compound Glycyrrhizin Tablets and levocetirizine hydrochloride orally. After treatment of 4 weeks, the symptom score, skin lesion score and clinical efficacy of the two groups were compared. Results After treatment of 4 weeks, the control group clinical effective rate was 83. 72%, which was obviously lower than 95. 35% of the treatment group ( P < 0. 05 ) . The symptoms score of the treatment group was ( 0. 24 ± 0. 12 ) points, which was obviously lower than ( 0. 89 ± 0. 29 ) points of the control group ( P < 0. 05 ) . The skin lesion score of the treatment group was ( 0. 42 ± 0. 14 ) points, which was obviously lower than ( 1. 03 ± 0. 20 ) points of the control group ( P < 0. 05 ) . Conclusion Compound Glycyrrhizin Tablets combined with levocetirizine hydrochloride has better clinical efficacy in treating nerve dermatitis.%目的：探讨复方甘草酸苷片联合盐酸左西替利嗪治疗神经性皮炎的临床疗效。方法选择86例神经性皮炎患者，随机均分为治疗组及对照组，均给予咪唑斯汀、丙酸氯倍他索乳膏治疗，治疗组患者加用复方甘草酸苷片及盐酸左西替利嗪口服溶液。治疗4周后比较两组症状积分、皮损积分及临床疗效。结果治疗4周后，对照组患者临床有效率为83.72%，明显低于治疗组的95.35%，差异有统计学意义（ P<0.05）；治疗组症状积分为（0.24±0.12）分，明显低于对照组的（0.89±0.29）分，差异有统计学意义（ P<0.05）；治疗组皮损积分为（0.42±0.14）分，明显低于对照组的（1.03±0.20）分，差异有统计学意义（ P<0.05）。结论复方甘草酸苷片联合盐酸左西替利嗪治疗神经性皮炎的临床疗效较好。
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