OBJECTIVE:To understand the pharmacists’knowledge for the rational drug use in the elderly,and to provide ref-erence for promoting the role of pharmacists in it. METHODS:A questionnaire was designed according to the Beers Criteria(2012 edition)to investigate the situation of pharmacists’(who were from some third-grade class-A hospitals in Guangzhou and some sec-ond-grade class-A hospitals in Foshan)knowledge for rational drug use in the elderly,and the data was statistically analyzed. RE-SULTS:Totally 190 questionnaires were sent out,and 176 were recycled with effective recovery of 92.63%. In the investigation, 30.11% of the pharmacists knew the knowledge well,23.30% was poor,and the rest was moderate. From 20 questions,the cor-rect answer rate more than 80% was only 5. Pharmacists in clinical pharmacy department showed higher score than those in non-clinical pharmacy department,the difference was statistically significant(P0.05). CONCLUSIONS:The pharmacists are not familiar with the rational use of drugs knowledge in the elderly well,and the understanding is related to working department,professional title and working time. It is necessary to strengthen the training and examination of pharmacists in rational drug use in the elderly,value and develop the construction of clinical pharmacy for the elderly actively.%目的：了解药师对老年人合理用药知识的掌握情况及影响因素，为促进药师在老年人合理用药中的作用发挥提供参考。方法：根据2012版Beers标准设计问卷，调查广州市部分“三甲”医院和佛山市部分“二甲”医院的药师对老年人合理用药知识的掌握现状，并就调查结果进行统计和分析。结果：共发放调查问卷190份，回收有效问卷176份，有效回收率为92.63％。受访药师中，答题较好的占30.11％，答题差的占23.30％，其余答题一般。20道题目中，答题正确率超过80％的仅5题。其中临床药学部门受访药师较非临床药学部门受访药师得分高，差异有统计学意义（P＜0.05）；职称越高、工作时间越久的受访药师得分越高，不同职称、工作时间的受访药师得分差异有统计学意义（P＜0.05）；而不同等级医院、不同学历的受访药师得分差异无统计学意义（P＞0.05）。结论：药师对老年人合理用药知识掌握一般，且其掌握情况与工作部门、职称、工作时间存在相关性。医院应加强药师关于老年人合理用药知识的培训和考核，重视并积极针对老年人开展以合理用药为中心的临床药学工作。
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