首页> 中文期刊> 《中国药房》 >缩宫素联合复方益母草口服液治疗人工流产术后出血的临床观察

缩宫素联合复方益母草口服液治疗人工流产术后出血的临床观察

         

摘要

OBJECTIVE:To observe therapeutic efficacy of Compound Leonurus japonicus oral solution in the treatment of hemorrhage after artificial abortion and its effect and safety on normal menstruation recovery. METHODS:100 cases of artificial abortion selected and randomly divided into treatment group and control group,with 50 cases in each group. Control group re-ceived oxytocin intramuscularly after surgery,10 U/time,12 h/time,for 3 times;treatment group was additionally given Com-pound L. japonicus oral solution,2 piece/time,3 times/d,for 5 days,on the basis of control group. Metrorrhagia duration,hemor-rhage amount,normal menstruation recovery and duration of abdominal pain and ADR were all observed in 2 groups. RESULTS:The metrorrhagia duration [(5.38±0.95)d] of treatment group was significantly lower than that [(8.58±1.32)d] of control group, with statistical significance(P<0.05);hypomenorrhea cases(24 cases)of treatment group was higher than those(9 cases)of con-trol group;menorrhagia cases(8 cases)was lower than those(24 cases)of control group;with statistical significance(P<0.05). The normal menstruation recovery time [(27.34±3.87)d] of treatment group was significantly shorter than that [(40.13±2.58)d] of control group,with statistical significance(P<0.05);the duration of abdominal pain [(2.85±0.89)d] in treatment group was sig-nificantly shorter than [(5.02 ± 1.33)d] in control group,with statistical significance (P<0.05).Obvious ADR was not found in both groups. CONCLUSIONS:Compound L. japonicus oral solution is effective in the treatment of hemorrhage after artificial abor-tion,can significantl shorten metrorrhagia duration and hemorrhage amount,recover normal menstruation early,improve the symp-toms of abdominal pain after operation and is easy to take and good safety.%目的:观察缩宫素联合复方益母草口服液治疗人工流产术后出血的疗效、安全性及对正常月经恢复的影响。方法:选取人工流产患者100例,按随机数字表法分为治疗组和对照组,各50例。对照组患者在术后采用缩宫素肌内注射,10 U/次,q12 h,注射3次;治疗组患者在对照组的基础上加用复方益母草口服液,20 ml/次,3次/d,服用5 d。观察两组患者子宫出血持续时间、出血量、正常月经恢复时间及腹痛持续时间及不良反应。结果:治疗组患者子宫出血持续时间为(5.38±0.95)d,明显低于对照组的(8.58±1.32)d,差异有统计学意义(P<0.05);治疗组患者出血量少者(24例)高于对照组(9例),量多者(8例)低于对照组(24例),差异具有统计学意义(P<0.05);治疗组患者正常月经恢复时间为(27.34±3.87)d,显著短于对照组的(40.13±2.58)d,差异具有统计学意义(P<0.05);治疗组患者腹痛持续时间为(2.85±0.89)d,明显短于对照组的(5.02±1.33)d,差异有统计学意义(P<0.05)。两组患者均未见明显不良反应。结论:复方益母草口服液治疗人工流产术后出血疗效显著,可明显缩短术后子宫出血时间,减少出血量,较早恢复正常月经时间,改善人工流产术后腹痛症状,服用方便且安全性较好。

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