目的:评价某“三甲”医院抗抑郁药的应用情况.方法:对某“三甲”医院2006-2011年抗抑郁药的销售金额、用药频度(DDDs)等进行回顾性统计、分析.结果:该院抗抑郁药销售金额呈逐年上升趋势,由2006年的110.41万元增加到2011年的431.93万元,增幅达292％.其中,选择性5-羟色胺(5-HT)再摄取抑制剂(SSRI)稳居第1位,5-HT及去甲肾上腺素再摄取抑制剂(SNRI)销售金额增长最快,而三环类抗抑郁药(TCA)的销售金额一直处于较低水平.所应用的15个品种中,年销售金额以舍曲林、帕罗西汀、文拉法辛一直处于较高水平,度洛西汀销售金额增长最快.结论:该院所应用的抗抑郁药以新型抗抑郁药为主流.%OBJECTIVE: To evaluate the utilization of antidepressants in a third-grade class-A hospital. METHODS: The utilization of antidepressants in a third-grade class-A hospital during 2006—2011 were analyzed retrospectively in tersm of consumption sum, DDDs, etc. RESULTS: The consumption sum of antidepressants increased year by year, from 1 104 100 yuan in 2006 to 4 319 300 yuan in 2011 with growth rate of 292%. SSRI kept taking up the first place; the consumption sum of SNRI increased most quickly, while that of TCA had been falling behind. Among 15 types of drug used, annual consumption sum of ser-traline, paroxetine and venlafaxine were comparatively high, and that of dutoxetine increased most quickly. CONCLUSION: The main antidepressants in our hospital are the new antidepressants.
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