Objective To explore clinical significance of prenatal heart guardianship for prognosis of newborn. Methods A total of 50 pregnant women as study subjects received non-stress test since the 36th gestational week, 25 cases with stress reactions as control group, and 25 cases without stress reactions as observation group. Comparison were made on newborn asphyxia rate and incidence of accidents between two groups. Results There was no newborn deaths in two groups. The observation group had a higher newborn asphyxia rate as 68.00% than 16.00% in control group, a higher incidence of accidents as 72.00% than 20.00%in control group, and differences had statistical significance (P<0.05). Conclusion Prenatal heart guardianship shows great significance for prognosis of newborn, decreasing asphyxia rate and incidence of accident, which also can monitor fetal situation effectively, avoid accident and provide theoretical support in clinical. So this method is worth promotion.%目的：探究产前胎心监护对新生儿预后的临床意义。方法50例孕妇作为研究对象，自妊娠36周起进行无应激试验检查，将有应激反应的25例孕妇作为对照组，将无任何应激反应的25例孕妇作为观察组。对比两组新生儿窒息率和意外情况的发生率。结果两组均无新生儿死亡。观察组新生儿窒息率68.00%高于对照组16.00%，意外发生率72.00%高于对照组20.00%，差异均具有统计学意义(P<0.05)。结论产前胎心监护对新生儿预后，及降低新生儿的窒息率和意外发生率具有较大的意义，能及时有效的监测胎儿情况，避免意外发生，为临床提供了理论支持，值得推广。
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