首页> 中文期刊> 《中国实用医药》 >脑出血术后应用依达拉奉疗效分析

脑出血术后应用依达拉奉疗效分析

         

摘要

Objective To observe the curative effect of edaravone injection in the treatment of patients after cerebral hemorrhage operation.Methods A total of 78 patients after cerebral hemorrhage operation were randomly divided into treatment group (39 cases) and control group (39 cases). The control group received conventional treatment, and the treatment group received additional 30 mg of edaravone injection for treatment. National institutes of health stroke scale (NIHSS) was applied before treatment and in 2 and 4 weeks after treatment, and Barthel index (BI) was applied after 3 months. The scores were statistically analyzed.Results The treatment group had NIHSS scores in 2 and 4 weeks as respectively (11.7±3.5) and (8.9±3.1) points, and those of the control group were (15.7±4.6) and (13.2±3.4) points. The difference between the two groups had statistical significance (P<0.01). After 3 months, the excellent rate of BI was 61.54% in the treatment group, and its effective rate was 84.62%. The control group had excellent rate as 38.46% and effective rate as 64.10%. The difference between the two groups had statistical significance (P<0.01).Conclusion Edaravone can accelerate rehabilitation of neurological function after cerebral hemorrhage operation, with safety and effectiveness.%目的:观察依达拉奉注射液应用于脑出血术后患者的疗效。方法78例脑出血术后患者随机分为治疗组(39例)和对照组(39例)。对照组给予常规治疗,治疗组在常规治疗基础上加用依达拉奉注射液治疗。分别于治疗前及治疗后2、4周进行神经功能缺损评分(NIHSS),3个月后行日常生活能力评分(BI),并进行统计学分析。结果治疗组治疗2、4周NIHSS分别为(11.7±3.5)、(8.9±3.1)分;对照组NIHSS分别为(15.7±4.6)、(13.2±3.4)分,两组比较差异有统计学意义(P<0.01)。3个月后治疗组BI显效率为61.54%、有效率为84.62%;对照组BI显效率为38.46%、有效率为64.10%,两组比较差异有统计学意义(P<0.01)。结论依达拉奉能促进脑出血术后患者的神经功能康复,且安全有效。

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