Objective:To explore the clinical curative effect and safety of operative treatment and non-operative treatment in uterine fibroid combined with pregnancy.Methods:68 patients with uterine fibroid combined with pregnancy were selected,in which 50 cases of cesarean section at the same time with hysteromyomectomy as the operation group,18 cases of vaginal spontaneous labor as the non operative group.45 patients without uterine fibroid with caesarean section at the same time were selected as the control group 1,6 patients without uterine fibroid with vaginal labor at the same time were as the control group 2. Results:The intrapartum bleeding volumes of the operation group and the non operative group,the control group 1 were compared, the differences were not significant(P>0.05).The intrapartum bleeding volumes of the control group 2 and the non operative group were compared,the difference was significant(P<0.05).Conclusion:According to the concrete condition,we choose delivery mode when uterine fibroid combined with pregnancy.If giving cesarean section,it is safe and effective to remove the uterine fibroid at the same time.%目的：探讨手术治疗与非手术治疗子宫肌瘤合并妊娠的临床效果及安全性。方法：收治子宫肌瘤合并妊娠患者68例，其中50例行剖宫产的同时行子宫肌瘤切除术，为手术组，18例阴道自然分娩，为非手术组。收治同期无子宫肌瘤行剖宫产患者45例作为对照组1，同期无子宫肌瘤行阴道分娩患者6例作为对照组2。结果：手术组与非手术组、对照组1产时出血量比较，差异均无统计学意义(P＞0.05)。对照组2与非手术组产时出血量比较，差异有统计学意义(P＜0.05)。结论：子宫肌瘤合并妊娠时根据具体情况来选择分娩方式，若行剖宫产术时，同时将子宫肌瘤一并切除是安全、有效的。
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