目的：对比分析2005—2014年中日友好医院住院患者中原发性肺癌患者的病理类型、年龄、性别的差异，以初步了解近10年本院住院肺癌患者的流行病学特征。方法调查2005—2014年在中日友好医院初次住院的原发性肺癌患者的临床资料，对肺癌病理类型构成、发病年龄、性别分布进行统计分析。结果本研究纳入2005—2014年初次住院的原发性肺癌患者共4114例，明确病理诊断3183例，临床诊断931例。肺腺癌患者构成比最高，占52.25％（1663/3183），男性患者例数是女性的1.98倍（2734/1380）。高发年龄为56~75岁，占60.73％（2499/4114）。2005—2014年各年病理类型构成比（χ2＝27.277，P ＝0.449）、各年龄段构成比（Z ＝0.573，P ＝0.999）比较，差异均无统计学意义。男女患者年龄段构成比比较，差异无统计学意义（χ2＝0.152，P ＝0.879）；2005—2014年各年份男女患者构成比比较，差异无统计学意义（χ2＝6.446，P ＝0.695）。Spearman 相关分析显示，56~65岁患者构成比与年份呈正相关（rs ＝0.806，P ＝0.005）。结论中日友好医院近10年收治住院原发性肺癌患者例数呈逐年增长趋势，腺癌构成比最高，其次是鳞癌、小细胞肺癌。高发年龄段为56~75岁；男性鳞癌比例高于女性。%Objective To make a comparative study on pathological pattern,age and gender of inpatients with primary lung cancer in China - Japan Friendship Hospital from 2005 to 2014,in order to investigate the epidemiologic features of inpatients with lung cancer in the hospital in the past 10 years. Methods We made an investigation on the clinical data of patients with primary lung cancer who were firstly admitted into China - Japan Friendship Hospital from 2005 to 2014. Statistical analysis was made on the pathological types of lung cancer,onset age and gender distribution. Results A total of 4 114 patients with primary lung cancer who were firstly admitted into the hospital from 2005 to 2014 were recruited,with pathological diagnosis for 3 183 and clinical diagnosis for 931 patients. The patients with lung adenocarcinoma accounted for 52. 25% (1 663 / 3 183) with the highest proportion,and the number of males was 1. 98(2 734 / 1 380)times that of females. The peak onset age range was 56 - 75,and the patients of this age range accounted for 60. 73% (2 499 / 4 114). The pathological type distribution was not significantly different among different years( χ2 = 27. 277,P = 0. 449),and the age distribution was not significantly different among different years( Z = 0. 573,P = 0. 999). Age distribution was not significantly different between males and females(χ2 = 0. 152,P = 0. 879),and gender distribution was not significantly different among different years(χ2 = 6. 446,P= 0. 695). Rank correlation analysis showed that distribution of 56 - 65 age group was positively correlated with year( rs =0. 806,P = 0. 005). Conclusion The number of primary lung cancer patients admitted by China - Japan Friendship Hospital in the past 10 years is increasing,and prevalence is highest in adenocarcinoma,second highest in squamous carcinoma and third highest in small cell lung cancer. The peak onset age range is 56 - 75. Males are higher than females in the prevalence of squamous carcinoma.
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