摘要:Objectives To investigate the the clinical efficacy of continuous blood purification ( CBP) for the patients with acute myocardial infarction complicated with severe heart failure.Methods 72 patients with acute myocardial infarction and severeheart failure received CBP treatment, mean arterial pressure( MAP) , heart rate ( HR) , respiratory rate ( RR) , urine volume, left ven-tricular end-diastolic diameter ( LDV) , left ventricular ejection fraction ( EF) , APCHE-II scores and dosages of vasoactive drugs be-fore and after CBP were observed and statistically analyzed.Results In the 72 patients, 52 survived and 20 died, the curative effi-ciency was72.2%.After receiving CBP therapy, APACHE-II score significantly lower (P<0.05,P<0.01), MAP and urine vol-ume were improved, HR, RR and dosage of vasoactive drugs were reduced, LDV were shortening, EF were increasing.Conclu-sions The therapeutic effect of continuous blood purification on acute myocardial infarction with severe heart failure is significant.%目的:探讨连续性血液净化( CBP)治疗急性心肌梗死合并重症心力衰竭的临床疗效。方法收集应用CBP治疗72例急性心肌梗死重症心力衰竭患者的临床资料,动态观察并对CBP治疗前后平均动脉压( MAP)、心率( HR)、呼吸频率( RR)、尿量、左室舒张末径( LDV)、左室射血分数( EF)、APACHE-Ⅱ评分及血管活性药的使用情况进行比较分析。结果52例救治成功,20例死亡,成功率72.2%;治疗后APACHE-Ⅱ评分较治疗前明显降低(P<0.05,P<0.01),MAP升高、HR下降、尿量增多、血管活性药用量减少,左室舒张末径(LDV)缩短,左室射血分数(EF)增加。结论 CBP能有效救治部分心肌梗死合并重症心力衰竭患者。