Objectives To investigate the the clinical efficacy of continuous blood purification ( CBP) for the patients with acute myocardial infarction complicated with severe heart failure.Methods 72 patients with acute myocardial infarction and severeheart failure received CBP treatment, mean arterial pressure( MAP) , heart rate ( HR) , respiratory rate ( RR) , urine volume, left ven-tricular end-diastolic diameter ( LDV) , left ventricular ejection fraction ( EF) , APCHE-II scores and dosages of vasoactive drugs be-fore and after CBP were observed and statistically analyzed.Results In the 72 patients, 52 survived and 20 died, the curative effi-ciency was72.2%.After receiving CBP therapy, APACHE-II score significantly lower (P<0.05,P<0.01), MAP and urine vol-ume were improved, HR, RR and dosage of vasoactive drugs were reduced, LDV were shortening, EF were increasing.Conclu-sions The therapeutic effect of continuous blood purification on acute myocardial infarction with severe heart failure is significant.%目的：探讨连续性血液净化（ CBP）治疗急性心肌梗死合并重症心力衰竭的临床疗效。方法收集应用CBP治疗72例急性心肌梗死重症心力衰竭患者的临床资料，动态观察并对CBP治疗前后平均动脉压（ MAP）、心率（ HR）、呼吸频率（ RR）、尿量、左室舒张末径（ LDV）、左室射血分数（ EF）、APACHE－Ⅱ评分及血管活性药的使用情况进行比较分析。结果52例救治成功，20例死亡，成功率72．2％；治疗后APACHE－Ⅱ评分较治疗前明显降低（P＜0．05，P＜0．01），MAP升高、HR下降、尿量增多、血管活性药用量减少，左室舒张末径（LDV）缩短，左室射血分数（EF）增加。结论 CBP能有效救治部分心肌梗死合并重症心力衰竭患者。
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