Sleep has a closely relationship with epilepsy. Seizures can disrupt sleep architecture,sleep disorders may lead to poorly controlled seizures. Along with the research development of the relationship between sleep and epilepsy,certain internal relations between REM sleep and intractable epilepsy become clear. This paper reviewed the relationship between REM sleep and intractable epilepsy,and provided a reference for diagnosis in intractable epilepsy.%癫痫与睡眠关系密切，癫痫发作可以扰乱睡眠，睡眠紊乱可导致癫痫的控制恶化。随着癫痫与睡眠关系的研究不断深入，逐渐认识到快速眼动睡眠（REM 睡眠）与难治性癫痫之间可能存在一定的内在联系。本文通过综述 REM 睡眠与难治性癫痫的关系，以期对难治性癫痫的诊断提供参考。
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