Objective To discuss the diagnostic value of pituitary MRI in patients with idiopathic hypogonadotropic hypogonadism ( IHH ) . Methods Clinical data and MRI of 51 patients diagnosed as IHH in the General Hospital of PLA from May 2004 to May 2010 were retrospectively analyzed. Results The mean age of the IHH patients was ( 17. 6 ±5. 2 ) . Of the 51 patients, 15 cases were accompanied by Kallmann syndrome. 33 cases ( 64.1% ) had abnormal MRI findings, and 28 cases had hypoplastic pituitary, accounting for 84. 8% , 15 cases had absent olfactory bulbs, accounting for 45. 5% , 11 cases had hypo-plastic olfactory sulci, accounting for 33. 3% and four cases had absent olfactory sulci, accounting for 12. 1%. Conclusion MRI shows small pituitary volume and dysplasia olfactory in IHH patients, making IHH a disease having its own features. If clinical and laboratory examinations can be combined with MRI, early diagnosis might be achieved.%目的 探讨垂体磁共振成像(MRI)在男性特发性低促性腺激素型性腺功能减退症(IHH)诊断中的应用价值.方法 回顾性分析2004年5月-2010年5月解放军总医院收治的51例临床诊断为男性IHH患者的临床资料和MRI表现.结果 51例IHH患者就诊时平均年龄为(17.6±5.2)岁,其中15例伴有嗅觉减退或消失.33例(64.7%)垂体MRI有异常发现,其中28例垂体体积小,占异常者的84.8%(28/33);15例嗅球未见显示,占45.5%(15/33);11例嗅沟发育不全,占33.3%(11/33);4例嗅沟未见显示,占12.1%(4/33).结论 IHH患者的MRI表现为垂体体积小及部分患者可以合并嗅器发育不良,具有一定特征性;如同时结合临床及实验室检查,可达到早期诊断的目的.
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