Objective To evaluate the efficacy of general anesthesia with SLIPA laryngeal mask airway with tumescent anesthesia in patients abdominal liposuction. Methods 160 ASAⅠ-Ⅱpatients of fe⁃males,aged 20-35years,weighing 56-78 kg,abdominal liposuction under general anesthesia,were randomly divided into 2 groups (n=80 each).Group Ⅰ received combined intravenous-inhalational anesthesia with endotracheal tube.Group Ⅱ received combined intravenous-inhalational anesthesia with SLIPA laryngeal mask airway then undergoing abdominal liposuction with tumescent anesthesia. HR was maintained at 50-100bpm,MAP was maintained at the preoperative baseline level (increase or decrease amplitude <20% of the baseline level) during operation and in postanesthesia care unit (PACIU) and vasoactive drugs (atropine,esmolol,efedrina or urapidil) were given when necessary.The patients received patient-controlled intravenous analgesia with sufentanil (background infusion 1.5 ml/h, bolus dose2 ml,lockout interval 15 min) after operation and VAS score was maintained at≤2.The re⁃quirement for vasoactive drugs during operation and in PACU,PACU stay length,and consumption of analgesics and occurrence of nausea and vomiting within 24h after operation were recorded. Results Compared with groupⅠ,the requirement for all vasoactive drugs during operation and in PACU was significantly reduced,PACU stay length was significantly shortened,and the consumption of analge⁃sics and incidence of nausea and vomiting were significantly reduced in groupⅡ(P<0.05). Conclu⁃sion general anesthesia with SLIPA laryngeal mask airway with tumescent anesthesia provides better efficacy with fewer complications and less consumption of postoperative analgesics than general an⁃esthesia with endotracheal tube in patients abdominal liposuction.%目的：评价SLIPA喉罩下全麻联合局部肿胀麻醉用于脂肪抽吸术的效果。方法：择期行腰腹脂肪抽吸术的患者80例，女性，年龄20～35岁，体重56～78kg，ASA分级Ⅰ～Ⅱ级，采用随机数字表法，将其随机分为2组（n=80）。Ⅰ组在气管插管下行静吸复合麻醉；Ⅱ组在SLIPA喉罩下全麻联合局部肿胀麻醉。术中和麻醉恢复室（PACU）停留期间维持HR50～100bpm，维持MAP波动幅度不超过基础值的20%。必要时给予血管活性药物（阿托品、艾司洛尔、麻黄碱和乌拉地尔）。术后采用舒芬太尼行PCIA（背景输注速率为1.5ml/h，PCIA量为2ml，锁定时间为15min），维持VAS评分≤2分。记录术中和PACU停留期间血管活性药物的使用情况；记录PACU停留时间；记录术后24h内PCIA药物用量和恶心呕吐的发生情况。结果：与Ⅰ组比较，Ⅱ组术中及PACU停留期间各血管活性药物的使用率降低，PACU停留时间缩短，PCIA药物用量减少，术后恶心呕吐发生率降低（P<0.05）。结论：喉罩下全麻联合局部肿胀麻醉下全麻用于脂肪抽吸术麻醉效果较好，并发症少，术后镇痛药物用量少，优于气管插管下全麻。
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