为研究日粮中低剂量镉对蛋鸡生产性能和血清、肝肾抗氧化能力的影响,将192羽巴布考克B300蛋鸡随机分为4组,每组3个重复.对照组饲喂玉米-豆粕型基础日粮,试验组日粮为在基础日粮中分别添加5、10、20 mg/kg的镉(氯化镉形式,CdCl2·2.5H2O),试验期9周.结果表明:在1～3、4～6、7～9周,试验组的产蛋率、日采食量均低于对照组(P＞0.05)；各组在第7～9周时的采食量显著低于1～3周(P＜0.05)；血清中GSH-Px、GST、GR酶活力对镉不敏感(P＞0.05),随镉添加量升高肝肾中GSH-Px活力先升后降,试验组肝肾中总巯基含量较对照组有显著升高(P＜0.05)；血清和肝肾中总SOD、CuZn-SOD、CAT活力随镉添加量升高呈先升后降的趋势；血清和肝肾中MDA、NO含量随着镉添加量的升高显著升高(P＜0.05),总抗氧化能力均呈下降趋势.试验结果证实,镉可引起产蛋鸡体内抗氧化功能受损,机体产生氧化应激,并可能由此导致蛋鸡的生产性能下降.%This experiment was conduct to investigate the effects of low -levels of dietary cadmium on production performance and antioxidative parameters in serum, liver and kidney of laying hens. One hundred and ninety two 40-w-old Babcock B-300 laying hens were randomly divided into four groups with three replicates per group and 16 laying hens per replicate. The diet of control group was a basal corn -soybean meal diet. The experimental diet was supplemented with cadmium (CdCl2 ·2.5H2O) 5 mg/kg,10 mg/kg and 20 mg/kg into basal diet, respectively. The experiment lasted for 9 weeks. The results showed that in 1-3, 4-6 and 7-9 week, the laying rate, ADFI of three trail group were lower than those of control group, in 7-9 week, the ADFI of all groups were lower than that in 1-3 week (P<0.05), GSH-Px, GST, GR in serum were not sensitive to the cadmium (P>0.05), GSH-Px activity in liver and kidney first increased and then decreased with the added level of cadmium increased, sulfhydryl levels of trail group in liver and kidney were higher than those of control group (P<0.05), the activity of total SOD, CuZn-SOD and CAT in serum, liver and kidney declines from 5 mg/kg, 10 mg/kg and 20 mg/kg group, the content of MDA and NO were significantly increased with the cadmium-added level increased (P<0.05), while T-AOC significantly decreased. These results indicated that cadmium could cause injury of body antioxidation system and induce oxidant stress of laying hens, consequently lead to a decrease of production performance of laying hens.
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