Objective To analyze the clinical distribution and drug resistance of pathogens of intravascular catheter-related bloodstream infections and to guide the treatment of intravascular catheter-related bloodstream infections.Methods A total of 45 patients with intravascular catheter-related bloodstream infections were analyzed retrospectively for clinical distribution and drug resistance.Results A total of 47 pathogens were detected in 45 patients,of which Gram-positive bacteria accounted for 38.29％,Staphylococci accounted for 25.53％,Gram-negative bacteria accounted for 34.04％,Acinetobacter and Enterobacteriaceae-based accounted for 12.76％ and 14.89％,and fungi accounted for 27.66％.The resistant rates of Gram-positive bacteria to teicoplanin and vancomycin were 0,and that to rifampicin and tetracycline were 29.41％ and 47.06％.The resistant rates of Gram-negative bacteria against amikacin,imipenem were 43.75％ and 37.50％.A strain of Candida tropicalis resistant to fluconazole,itraconazole,and voriconazole was found.Conclusion To understand the clinical distribution and drug resistance of pathogens causing intravascular catheter-related bloodstream infections,it is helpful to guide the treatment of intravascular catheter-related bloodstream infections.%目的 分析血管内导管相关性血流感染的临床分布特征及耐药性,指导血管内导管相关性血流感染的治疗.方法 对医院确诊为血管内导管相关性血流感染的45例患者进行回顾性分析临床分布特征及其耐药性.结果 45例患者共检出47株病原菌,其中革兰阳性菌占38.29％,以葡萄球菌属为主,占25.53％,革兰阴性菌占34.04％,以不动杆菌属和肠杆菌科菌属为主,分别占12.76％和14.89％,真菌占27.66％;革兰阳性菌对替考拉宁和万古霉素耐药率均为0,对利福平和四环素耐药率为29.41％和47.06％;革兰阴性菌对阿米卡星和亚胺培南的耐药率为43.75％和37.50％;发现1株对氟康唑、伊曲康唑和伏立康唑耐药的热带念珠菌.结论 了解血管内导管相关性血流感染临床分布特征及耐药性,有助于指导血管内导管相关性血流感染的治疗.
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