Objective To explore the potential relationship between sleep disorders and volume of epicardial adipose tissue (EAT).Methods Eighty-two cases of MHD patients with dialysis more than 3 months were chosen in our hemodialysis center from January 2013 to August 2014 and were divided into two groups(PSQI≤5 and PSQI >5) according to PSQI score.PSQI,ESS,volume of epicardial fat tissuewere observe,and explore the relationship of sleep quality and epicardial fat volume.Results There were nosignificant differences in the age,gender between two groups (P >0.05).The CRP and leptin in sleep disorder group was higher than that in the control group(P <0.05).EAT volume of sleep disorder group and control group were(170.0 ±17.0)cm3 and (141.9 ±22.4)cm3 ,respectively,which had statistical difference(P <0.05).Conclusions EAT volume change and sleep disorder exist a certain relationship in patients with maintenance hemodialysis.%目的探讨血液透析患者睡眠障碍与心包脏层脂肪组织（EAT）体积的潜在关系。方法选择透析时间超过3个月且病情比较稳定的维持性血液透析（MHD）患者82例，根据匹兹堡睡眠质量量表（PSQI）积分分为两组，睡眠障碍组（PQSI ＞5分）和对照组（PQSI≤5分）。观察两组 PQSI、爱泼沃思嗜睡量表（ESS）、心包脏层脂肪的体积，并探讨血液透析患者睡眠质量与心包脏层脂肪的体积的相关性。结果两组患者性别和年龄均差异无统计学意义（P ＞0．05），但睡眠障碍组患者 CRP，瘦素较对照组更高，差异有统计学意义。睡眠障碍组EAT 体积（170．0±17．0）cm3，对照组 EAT 体积（141．9±22．4）cm3，两组 EAT 差异有统计学意义（P ＜0．05）。结论维持性血液透析患者发生睡眠质量与 EAT 体积的改变存在相关关系。
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