Objective To assess the clinical efficacy of renal artery stent treatment for severe atherosclerotic renalarterystenosis(ARAS).Methods 106patientswithatherosclerosisunderwentpercutaneoustransluminalrenal angioplasty and stenting( PTRAS) were rolled in,which included 60 male and 47 female patients with renal artery ste-nosis >50%in diameter.The followed-up time was 12 months.The level of patient's blood pressure,serum creatinine and estimated—glomerular filtration rate( eGFR) were detected.Results During 12 months of follow up,both systol-ic and diastolic blood pressure level were significantly decreased(P<0.05),and less antihypertensive medication was taken(P<0.05).EGFR remained stable in the process of follow-up.(P<0.05).Conclusion PTRAS is effective for the treatment of hypertension and keep the renal function stabilize in ARAS patients.%目的评估肾动脉支架置入治疗严重动脉粥样硬化性肾动脉狭窄患者的临床疗效。方法收集接受肾动脉支架治疗的106例肾动脉狭窄患者，其中男性60例，女性46例，肾动脉狭窄直径＞50％，因严重高血压或伴有肾功能不全而进行肾动脉支架置入术，采集患者的血压、抗血压药物种类、肌酐、估计肾小球滤过率（ eGFR）等临床资料，术后随访12个月。观察手术对患者血压、肾功能影响。结果与术前基线值比较，血压随访时显著下降，并且服降压药种数减少（ P＜0．05）；eGFR在随访过程中保持稳定（ P＞0．05）。结论肾动脉支架重建血运能明显改善肾动脉狭窄患者的血压情况，术后患者的肾功能保持稳定。
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