Objective:To summarize the experience in surgical treatment for ulcerative colitis(UC).Methods:The clinical data of 36 patients with UC who underwent surgery in Renji Hospital,Shanghai Jiao Tong University School of Medicine from Jan 2008 to Jan 2013 were retrospectively analyzed.The surgical methods and prognosis were evaluated.Results:There were 23 ca-ses of selective operation which was total colectomy with ileal pouch-anal anastomosis(IPAA)in the first stage.Among the 23 cases,4 cases complicated with toxic megacolon were treated with intestinal obstruction catheter by endoscopy,and then under-went selective IPAA.There were 13 cases of emergency operation which was total colectomy with ileostomy in the first stage and IPAA in the second stage.Open surgery was done in 1 patient with perforation of digestive tract,1 patient with toxic mega-colon and 1 patient with history of abdominal operation,and laparoscopic surgery was done in the other 33 patients.None of the 36 cases had any severe perioperative complications.Conclusions:Indication of UC operation should be strictly controlled while safe operation method should be reasonably chosen.IPAA is a safe and effective method for selective operation and emergency surgery of UC.%目的：探讨溃疡性结肠炎（ulcerative colitis，UC）的手术适应症和安全的手术方式。方法：回顾分析2008年1月—2013年1月在上海交通大学医学院附属仁济医院施行手术的36例 UC 患者的临床资料，对其手术方法及预后等进行分析。结果：36例中择期手术23例，急诊手术13例。23例择期手术均为一期全结直肠切除＋回肠贮袋肛管吻合术（ileal pouch-anal anas-tomosis，IPAA）；其中4例合并中毒性巨结肠患者通过急诊结肠镜下留置肠梗阻导管暂时缓解症状，再择期行 IPAA。13例急诊手术患者均一期行全结肠切除＋回肠造口术，二期行 IPAA。36例患者中除1例消化道穿孔、1例中毒性巨结肠及1例有腹部手术史的患者行开腹手术，其余33例患者均行腹腔镜手术。36例患者均无严重围手术期并发症发生。结论：对于 UC患者，应严格掌握手术适应证，合理选择安全有效的手术方式。UC 择期手术、急诊手术中行 IPAA，均安全有效。
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