目的：探讨颈动脉超声在缺血性脑血管病（ischemic cerebrovascular disease，ICVD）患者颈动脉病变检测中的应用。方法：应用彩色多普勒超声对82例 ICVD 患者和40例健康体检者进行颈动脉超声检查并测定血管反应性（vascular reactivity， VR）。比较2组研究对象的颈动脉内"中膜厚度（intima-media thickness，IMT）、斑块总积分、斑块总面积及脑血流量等情况。结果：ICVD 患者中颈总动脉及颈内动脉重度狭窄组患者的血管内径（vessel diameter，VD）、IMT、收缩期最大血流速度（peak systolic velocity，PSV）、舒张末期最低血流速度（end-diastolic velocity，EDV）、平均血流速度（mean flow velocity，MFV）均显著高于对照组（P ＜0．01）；颈动脉无狭窄组患者及轻、中、重度狭窄组患者的 VR 均低于对照组（P ＜0．05）；ICVD 组患者 IMT、颈动脉斑块积分、斑块总面积显著高于对照组（P ＜0．01）。结论：应用颈动脉超声检测 ICVD 患者的颈动脉病变程度，有助于了解 ICVD 的不同状态以判断病程及预后，对 ICVD 的治疗具有重要意义。%Objective:To explore the application of carotid ultrasonography in detecting carotid artery lesions of patients with ischemic cerebrovascular disease(ICVD).Methods:Carotid ultrasonography and vascular reactivity(VR)were performed on 82 patients with ICVD and 40 health controls with Color Doppler Ultrasound.The ultrasonic indexes were statistically analyzed. The intima-media thickness(IMT)and the plaque score,the plaque total area and the cerebral blood flow volume of two groups were compared with each other.Results:Vessel diameter (VD),IMT,peak systolic velocity (PSV),end-diastolic velocity (EDV),mean flow velocity(MFV)in patients with severe stenosis of internal carotid artery and common carotid artery in ICVD group were significantly higher than those in control group,and the differences were statistically significant(P <0.01).VR in patients without stenosis and with mild,moderate and severe stenosis was lower than that in the control group(P <0.05).In ICVD group,IMT,carotid plaque score and plaque total area were significantly higher than those in the control group(P <0.01).Conclusions:The detection on degree of carotid lesions in patients with ICVD via carotid ultrasonography was conducive to understanding the status of ICVD,so as to determine the course and the prognosis.It was significant to clinical treatment of ICVD.
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