Objective:Thc research aims at studying the role of peripheral blood intcricukin 4 (IL-4) , intcricukin 8 (IL-8) and intcricukin 10 (IL-10) in asthma and chronic obstructive pulmonary disease (COPD). Methods: Use double-antibody sandwich enzyme-linked immunosorbent assam (ELISA) to detect the content of scrum IL-4, IL-8 and IL-10 in 50 cases of acute exacerbation of COPD (AECOPD) , 50 cases of paracmastic COPD, 50 cases of acute asthma, 50 cases of paracmastic asthma and 50 cases of healthy volunteers (healthy control group). Results: The levels of IL-4 and IL-8 in the scrum of the patients with acute asthma were significantly higher than that of the paracmastic asthma group(P<0. 01) , while the levels of scrum IL-4,IL-8 in these two groups were significantly higher than that in the healthy group (P展开▼