随着基因修饰小鼠的广泛使用，在饲养管理中必然会遇到一些新问题。文章以北京大学医学部实验动物科学部清洁级动物实验设施中饲养的基因修饰小鼠为对象，着重探讨其在饲养管理和使用中出现的问题，并加以分析，为建立基因修饰小鼠的管理规范奠定基础。%The genetically modified mice , as a helpful model , have been widely used in life scientific research . However, several new issues appeared subsequently with the wide application of the genetically modified mice .Here, we mainly discussed and analyzed the problems in the management and usage of genetically modified mice , which underlies the foundation for establishing management practice of the genetically modified mice .
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