支气管哮喘和慢性阻塞性肺疾病(COPD)是2种不同的慢性气道炎性反应性疾病,两者在病因、发病年龄、病理生理、治疗和预后方面存在差异.然而,临床发现部分具有慢性气道炎性疾病的患者可同时具有以上2种疾病的特点,临床多将其描述为哮喘—慢性阻塞性肺疾病重叠综合征(ACOS).2017全球哮喘防治创议(GINA)将其描述为哮喘—慢性阻塞性肺疾病重叠(ACO).已有的研究发现,ACO比单独的哮喘和慢性阻塞性肺疾病急性加重更加频繁,生活质量更差,肺功能下降更快及病死率更高,消耗更多医疗资源,而目前对于ACO的认识还处于一个初级阶段,相关研究也逐渐受到广泛关注,文章对哮喘—慢性阻塞性肺疾病重叠近年的研究进展进行阐述.%Bronchial asthma and chronic obstructive pulmonary disease ( COPD) are two kinds of chronic airway in-flammatory disease, but different in the age of onset, etiology, pathophysiology, treatment and prognosis. However, the clini-cal features of the two kinds of diseases can be found in the same patients with chronic airway inflammatory disease. It was de-scribed it as Asthma COPD overlaps (ACO)in GINA (Global Initiative for Asthma) in 2017. It has been found that ACO has more frequent exacerbations, worse quality of life, lung function declined faster, higher mortality and more consumption of medical resources than individual asthma and COPD, and the current knowledge of ACO is still in the primary stage, so the research progress of Asthma COPD overlap in recent years will be described.
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