目的：应用速度向量成像（ VVI）技术评价糖尿病患者颈动脉斑块形成后血管管壁运动力学的改变。方法应用速度向量成像技术对糖尿病颈总动脉有斑块者（糖尿病组，30例）及健康查体者（健康对照组，30例）进行分析，比较2组长轴切面管壁的运动矢量图、重建三维参数图，计算其最大切向运动速度（ Vs）、最大切向应变（ Smax ）及最大切向应变率（SRmax）。结果健康对照组长轴切向速度、应变、应变率曲线形态分别趋于一致；糖尿病组颈总动脉斑块处管壁切向速度、应变、应变率时间曲线变化大，峰值不定，变化无规律，部分斑块处管壁各位点达峰时间不同步。糖尿病组颈动脉Vs、Smax、SRmax[（15．22±11．50）×10-2cm/s、（2．66±1．01）％、（0．25±0．24）/s]，明显低于健康对照组[（30．32±10．24）×10-2cm/s、（4．49±1．34）％、（0．62±0．34）/s]（ P ＜0．05）。斑块肩部运动速度最大，纤维帽下方管壁运动速度最小，且上下游肩部管壁的应变、变变率高于纤维帽下方处管壁（ P ＜0．05）。结论糖尿病患者颈动脉粥样硬化斑块部位管壁运动的不同步性，表明VVI可以量化评价已发生血管重构的颈动脉管壁运动及其斑块稳定性。%Objective To evaluate changes of vascular wall motion mechanics of diabetic patients with carotid plaques applying the velocity vector imaging ( VVI) .Methods The research applied VVI in diabetes group ( patients with ca-rotid artery plaque, 30 cases) and normal control group (30 cases) to make retrospective analysis, which analyzed the long axis plane wall motion vector graph , reconstructed the parameters of the ion of 3D graph, and computed its maximum tangen-tial velocity (Vs), maximum tangential strain (Smax) and maximum tangential strain rate (SRmax).Vascular walls in upstream and downstream shoulders of the carotid artery plaque and beneath the fibrous cap were taken to measure the maximum tangen -tial velocity (Vs), maximum tangential strain (Smax) and maximum tangential strain rate (SRmax).Results In the diabetes group, the curve of tangential velocity , strain, and strain rate time of wall in carotid artery plaque changed significantly, while the peak changed irregularly , and the Smax of wall sites were not synchronized;the Vs[(15.22 ±11.50) ×102 cm/s], Smax [(12.66 ±1.01)%] and SRmax[(0.25 ±0.24)/s] of carotid artery were significantly lower than the normal control group [(30.32 ±10.24) ×10 -2 cm/s], Smax [(4.49 ±1.34)%] and SRmax [(0.62 ±0.34)/s] ( P <0.05).The velocity of walls in shoulder was the maximum , while the velocity of walls beneath the fibrous cap was the minimum , the strain and strain rate of wall in upstream and downstream shoulders of the carotid artery plaque was significantly higher than the ones beneath fi -brous cap ( P <0.05).Conclusion The wall motion in carotid atherosclerotic plaques is asynchronous , VVI can be applied to evaluate the wall motion of carotid artery of diabetic patients with vascular remodeling and the stability of the plaques .
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