目的 分析肝硬化合并胆囊结石患者的临床特征.方法 选择肝硬化合并胆囊结石患者32例为观察组,另选择肝硬化未合并胆囊结石患者33例为对照组,比较2组患者性别、年龄、肝功能分级、血浆白蛋白水平、门静脉内径宽度、内毒素水平、内毒素血症发生率及低密度血浆脂蛋白(Lp-X)阳性率.结果 观察组患者年龄≥60岁的比例高于对照组(P＜0.05),门静脉内径均值为(16.54±2.31)mm、白蛋白浓度为(28.34±3.23)g/L,与对照组相比差异均有统计学意义(P＜0.05),观察组患者内毒素水平(71.13±34.55)pg/ml高于对照组的(24.32±12.34)pg/ml(P＜0.05),内毒素血症发生率及Lp-X阳性率均高于对照组(71.88% vs 48.48%,56.26% vs 30.30%,P＜0.05).结论 年龄≥60岁,门静脉内径宽、白蛋白较低者更易发生胆囊钻石;合并胆囊结石患者内毒素血症发生率与Lp-X阳性率均较未合并者高.%Objective To analyze the clinical features of cirrhosis in patients with gallstones. Methods 32 patients with cirrhosis gallstones in the observation group, and 33 cases cirrhosis of the liver without gallstones were in the control group, the age,gender, liver function, serum albumin level, portal vein diameter width endotoxin levels, the positive rate and positive rate of Lp-X of two groups were compared. Results The rate of ≥60 years old patients was significantly higher than the control,the difference was statistically significant( P < 0. 05 ). Observation of patients with portal vein diameter mean ( 16. 54 ± 2. 31 ) mm,albumin concentration ( 28. 34 ± 3. 23 ) g / L, there were statistically significant compared with the control group( P < 0. 05 ). Toxin levels of the patients were (71.13 ± 34. 55 ) pg/ml, was significantly higher than the control group ( 24. 32 ± 12. 34 ) pg / ml,the difference had statistically significant P <0. 05 ). The positive rate of the incidence of endotoxemia and Lp-X was significantly higher than those in control group,the difference had statistically significant( 71. 88% vs 48. 48% ,56. 26% vs 30. 30% , P < 0. 05 ). Conclusion The patients with liver cirrhosis complicated by the high inci-dence of gallbladder stones, should take positive measures of prevention and treatment.
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