目的 探讨老年急性心肌梗死(AMI)患者血小板参数的临床意义.方法 对2007年3月-2010年11月收治的老年AMI患者84例(AMI组)与同期健康查体者90例(健康对照组)应用血细胞分析仪测定血小板(PLT)计数、血小板平均体积(MPV)和血小板分布宽度(PDW)值,并进行比较.结果 AMI组PLT低于健康对照组[(221±62)×109/L vs (280±32)×109/L],MPV和PDW高于健康对照组[分别为(10.30±1.08)fl vs (9.80±0.50)fl和(13.01±2.07)% vs (11.48±0.40)%],差异均有统计学意义(P＜0.05);并且AMI组PLT与MPV、PDW呈负相关(r=-0.341,r=-0.462,P均＜0.05).结论 急性心肌梗死患者PLT计数下降,MPV、PDW升高,血小板活化是AMI的独立危险因素.%Objective To investigate the clinical significance of platelet parameters in elderly acute myocardial infarction ( AMI) patients. Methods Apply US Kurt company TT-R1 type blood cells analyzer to determine PLT, MPV and PDW value in 84 elderly patients with AMI ( AMI group ) and 90 people at the same period ( healthy control group )from March 2007 to November 2010, recorded and analyzed these data. Results PLT of AMI group was lower than those of the healthy control group[ ( 221 ± 62 ) x 109/L vs ( 280 ± 32 ) x 109/L ], MPV and PDW are higher than those in the healthy control group [( 10.30±1.08)fl vs(9.80±0. 50 )fl and( 13.01 ±2.07)% vs ( 11.48 ±0.40)% ],the differences have statistical significant P <0.05 ); PLT were negatively correlated with MPV, PDW of AMI group( r = -0.341, r = -0.462, P <0.05 ). Conclusion PLT decreased, MPV and PDW were increased, during onset of acute myocardial infarction, activation of platelet is an independent risk factor of AMI.
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