Objective To evaluate the running status of Qinghai provincial measles laboratory network during 2012-2017.Methods To analyze serological and virological surveillance database developed in Qinghai provincial measles laboratory network in 2012-2017,and evaluate the indicators for the running status of measles laboratory network in Qinghai Province.Results It was shown that 5 763 suspected measles cases were reported in Qinghai Province during 2012-2017,and 4 167 serum samples were collected from suspected measles cases,the collection rate is 72.31％;among them,3 697 were IgM positive for measles and the positive rate was 88.72％;68 were IgM positive for rubella and the positive rate was 1.63％.And 515 throat swab specimens were collected from suspected measles cases,82 measles virus isolates were obtained and the positive rate was 15.92％.The result of sequencing and analysis showed that all the measles viruses belonged to genotype H1 and subgenotype H1a,which were predominant genotype circulated in China in recent years.In addition,Qinghai provincial measles network labs passed all the serological confirmatory test and proficiency test,and on-site review held by national or provincial measles laboratory and WHO during 2012-2017,respectively.Conclusions Qinghai provincial measles laboratory network has been established and running well.It provided important scientific basis for measles elimination in Qinghai province.%目的 评价青海省2012-2017年麻疹实验室网络的运转情况.方法 分析青海省2012-2017年麻疹实验室网络血清学和病毒学监测数据库,评价青海省麻疹实验室网络运转的各项指标.结果 青海省2012-2017年麻疹监测系统共报告疑似麻疹病例5 763例,采集血清标本4 167份,采集率72.31％;麻疹IgM抗体阳性3 697份,阳性率为88.72％;风疹IgM抗体阳性68份,阳性率为1.63％.共收集麻疹疑似病例咽拭子标本共515份,分离到麻疹病毒82株,阳性率为15.92％;经基因序列测定和分析,2012-2017年麻疹野病毒均属于H1基因型中的H1a基因亚型,为我国的优势流行基因型病毒.2012-2017年省级麻疹网络实验室均通过了国家级麻疹实验室年度血清标本盲样考核、血清复核及现场认证.结论 青海省麻疹实验网络运转良好,为青海省消除麻疹奠定了良好的实验室基础.
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