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缺血性结肠炎28例临床分析

         

摘要

背景:近年缺血性结肠炎的患病率呈增高的趋势,其临床表现不典型,并发症多,误诊率、死亡率高.目的:总结缺血性结肠炎的临床特征,以提高其诊治水平.方法:收集2005年8月~2010年7月中南大学湘雅二医院收治的28例缺血性结肠炎住院患者的资料,从年龄、基础疾病、临床表现、实验室检查、内镜下特点、治疗等方面进行回顾性分析.结果:缺血性结肠炎多发生于合并心血管疾病的女性老年患者,多为急性或亚急性起病,主要临床表现为腹痛,多数患者大便隐血试验阳性,结肠镜下可见黏膜充血、糜烂、溃疡形成,治疗后病情明显好转.结论:对有心血管疾病的老年患者出现腹痛、血便时,应考虑缺血性结肠炎的可能,及时行结肠镜检查进一步证实,并予以积极有效的治疗.%Background: The incidence of ischemic colitis tends to increase in recent years. The clinical manifestations of this disease are atypical, and the rates of complication, misdiagnosis and mortality are high. Aims: To summarize the clinical characteristics of ischemic colitis for improving its diagnosis and treatment. Methods: The clinical data including age,underlying disease, clinical manifestations, laboratory examinations, endoscopic features and treatment of 28 inpatients with ischemic colitis in The Second Xiangya Hospital of Central South University from August 2005 to July 2010 were analyzed retrospectively. Results: Ischemic colitis was more prevalent in elderly females with cardiovascular diseases, and the onset of disease was often acute or subacute. The prominent clinical manifestation was abdominal pain, and most patients had positive fecal occult blood test. Mucosal erythema, erosion and ulceration were seen under colonoscopy. After treatment, the condition of patient was obviously ameliorated. Conclusions: When abdominal pain and bloody stools are seen in elderly patients with cardiovascular diseases, ischemic colitis should be considered. Colonoscopy should be performed to confirm the diagnosis and effective therapy is administered.

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