瘘管是克罗恩病(CD)常见的一种并发症,往往导致患者生活质量明显下降.许多临床试验证实英夫利昔对瘘管型CD安全有效.对传统治疗方案无效者,早期规律给予英夫利昔可很好地控制疾病进展和复发.对单药治疗效果不佳者,联合英夫利昔和内外科治疗可提高疗效.本文就近年英夫利昔治疗瘘管型CD的研究进展作一综述.%Fistula is a common complication of Crohn's disease (CD), which always results in an obvious decrease of patients' life quality. Infliximab has been proved to be safe and effective for the treatment of CD with fistula on the basis of a plenty of clinical trials. For patients who have failed from traditional therapy, early and regular administration of infliximab could well control the progress and relapse of the disease. For patients failed to have a good response with infliximab alone, infliximab combined with surgery and other medical therapy can increase the efficacy. In this article, we reviewed the progress in study of infliximab in the treatment of fistula in CD.
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