Objectives:To explore the safe method of labor induction of scar uterus in the second trimester of pregnancy.Methods:80 patients with labor induction of scar uterus in the second trimester of pregnancy in our hospital from May 2014 to May 2016 were selected.These patients were divided into mifepristone combined with rivanol treatment group (combined treatment group,n =40) and simple rivanol treatment group (single treatment group,n =40).The uterine contraction launch time,delivery time,amount of vaginal bleeding,success rate,caul residual,incidences of adverse reactions of the two groups were statistically analyzed.Results:Compared with control group,the delivery time of combined treatment group was significantly shorter (P ＜ 0.05) and the amount of vaginal bleeding was significantly less (P ＜ 0.05).The success rate (100％,40/40) of combined treatment group was significantly higher than that of single treatment group (87.5％,35/40) (P ＜ 0.05).The fetal residual rate (10％,4/40) was significantly lower than that of single treatment group (27.5％,11/40) (P ＜ 0.05).The incidence of adverse reactions (5％,2/40) of combined treatment group was significantly lower than that of single treatment group (20％,8/40) (P ＜ 0.05).Conclusion:The effect of mifepristone combined with rivanol treatment of labor induction of scar uterus in the second trimester of pregnancy is better than simple rivanol treatment.It can effectively shorten the delivery time,reduce the amount of vaginal bleeding,improve the success rate of labor induction,reduce the residual rate and the incidence of adverse reactions.%目的:探讨瘢痕子宫孕中期引产的安全方法.方法:选取我院2014年5月至2016年5月收治的瘢痕子宫孕中期孕产患者80例,依据随机数字表法将这些患者分为利凡诺联合米非司酮治疗组(联合治疗组,n=40)和单纯利凡诺治疗组(单独治疗组,n=40)两组,对两组患者的宫缩发动时间、排胎时间、阴道出血量、引产成功、胎物残留情况、不良反应发生情况进行统计分析.结果:联合治疗组患者的排胎时间显著短于单独治疗组(P＜0.05);阴道出血量显著少于单独治疗组(P＜0.05);引产成功率100.0％ (40/40)显著高于单独治疗组87.5％ (35/40) (P ＜0.05),胎物残留率10.0％ (4/40)显著低于单独治疗组27.5％(11/40) (P ＜0.05);不良反应发生率5.0％ (2/40)显著低于单独治疗组20.0％ (8/40) (P ＜0.05).结论:瘢痕子宫孕中期引产中利凡诺联合米非司酮治疗效果较单纯利凡诺治疗好,更能有效缩短患者的排胎时间,减少患者的阴道出血量,提升患者的引产成功率,降低患者的胎物残留率及不良反应发生率.
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