Objectives:To investigate the pathogen distribution of female reproductive tract infection (RTI) in pregnancy and drug resistance of pathogenic bacteria infection,in order to provide reference for the treatment of RTI and maternal and child health.Methods:1249 pregnant women from May 2013 to May 2015 were selected and conducted RTI detection through vaginal or cervical secretions for species identification and susceptibility testing.Results:In the 1249 pregnant women,412 cases had RTI,an infection rate of 32.99％.The main infection diseases included vaginitis mycoplasma,chlamydia vaginitis,trichomonas vaginitis,bacterial vaginosis,gonorrhea,syphilis and etc.,with major causing pathogen being Candida,including Candida albicans,accounting for 85.44％ (352/412),Candida glabrata,accounting for 2.91％ (12/412),krusei,accounting for 5.58％ (23/412),Candida tropicalis,accounting for 1.94％ (8/412),and others.According to pathogen susceptibility testing,Candida albicans was more sensitive against the 5-fluorocytosine and amphotericin B,while had certain resistance against miconazole,ketoconazole and itraconazole,resistance rates of 36.50％,23.25％ and 18.5％ respectively,while glabrata,krusei,Candida tropicalis and others were more sensitive to antibacterial drugs used in the treatment of Candida.Conclusion:The incidence of RTI in pregnancy is relatively high,with the major pathogen being Candida,so infection screening should be paid attention to in clinical.%目的:探讨妊娠期女性生殖系统感染病原菌的分布以及耐药性分析,为妊娠期生殖系统感染患者的治疗和母婴的健康提供参考.方法:选取2013年5月至2015年5月期间医院的1249例妊娠期妇女为本次的研究对象,对所有妊娠期妇女的阴道或宫颈分泌物做生殖系统的感染检测,对被检出的菌种进行鉴定以及药敏试验.结果:在本次研究的1249例妊娠期妇女中,出现生殖系统感染的妊娠期妇女有412例,其生殖系统感染率为32.99％,主要感染的疾病有支原体性阴道炎、衣原体性阴道炎、滴虫性阴道炎、细菌性阴道病、淋病、梅毒等等,引起妊娠期生殖系统感染的主要病原菌为真菌中的念珠菌,经病原菌的鉴定试验发现患者主要感染的念珠菌有白色念珠菌,占85.44％(352/412),光滑念珠菌,占2.91％(12/412),克柔念珠菌,占5.58％ (23/412),热带念珠菌,占1.94％ (8/412),以及其他病原菌.对病原菌进行药敏试验发现白色念珠菌主要是对5-氟胞嘧啶和两性霉素B比较敏感,而对与咪康唑、酮康唑以及伊曲康唑都有一定的耐药性,其耐药率依次为36.50％、23.25％和18.5％,而光滑念珠菌、克柔念珠菌、热带念珠菌以及其他念珠菌对治疗过程中所使用的抗菌药物都比较敏感.结论:妊娠期女性生殖系统感染率比较高,其感染病原菌主要为念珠菌,在临床中要重视妊娠期女性生殖系统感染的筛查工作.
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