Objective To evaluate multidrug-resistant bacterial (MDRB) healthcare-associated infection (HAD in malignant tumor patients,so as to provide basis for the effective prevention and control measures.Methods Data on MDRB isolated from various specimens in Henan Tumor Hospital in January-December 2011 were analyzed retrospectively.Results A total of 2 562 pathogenic strains were isolated,449 (17.53％) of which were MDRB.Of all MDRB,305 (67.93 ％)were gram-negative bacteria,the isolation rate of Escherichia coli was the highest (54.57 ％,245 isolates),followed by Klebsiella pneumoniae (9.80％,44 isolates); gram-positive bacteria were 144 isolates (32.07％),the isolation rate of Staphylococcus aureus (11.80％,53 isolates) and Staphylococcus epidermidis (11.58％,52 isolates) were higher.MDRB infections were mainly concentrated on general surgery (26.73％,120isolates)and hepatobiliary surgery(21.83％,98 isolates) ; the major specimen was drainage fluid of pleuroperitoneal cavity(39.42％),followed by sputum (19.82％)and blood(19.16％).Conclusion HAI monitoring helps to realize MDRB infection and prevent outbreak of HAI.%目的 探讨肿瘤医院住院患者多重耐药菌(MDRB)医院感染情况,为制定有效的防控措施提供依据.方法 对河南省肿瘤医院2011年1-12月送检的各类标本分离的MDRB资料进行回顾性分析.结果 共分离细菌2 562株,其中MDRB449株,占17.53％.MDRB中,革兰阴性菌305株(67.93％),以大肠埃希菌检出率(54.57％,245株)最高,其次为肺炎克雷伯菌(9.80％,44株);革兰阳性菌144株(32.07％),以金黄色葡萄球菌(11.80％,53株)和表皮葡萄球菌(11.58％,52株)检出率较高.MDRB感染重点科室是普通外科(120株,26.73％)和肝胆外科(98株,21.83％);标本来源以胸(腹)腔引流液较多(39.42％),其次为痰液(19.82％)和血液(19.16％).结论 医院感染监测有助于了解医院MDRB感染情况和预防医院感染暴发.
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