Platycodin-D (PD) is the major monomer of triterpene saponins in the root of Platycodon grandiflorum. Recent studies have demonstrated that PD has a wide range of anti-tumor effect and its efficacy is satisfying. This article reviewed anti-tumor mechanisms of PD from the aspects of proliferation, apoptosis, invasion and metastasis, immune and anti-inflammation, etc., with a purpose to provide a theoretical basis and reference for the further development and better utilization of PD and taking its anti-tumor advantage.%桔梗皂苷-D(PD)是从桔梗中提取的一种三萜类单体。近年来研究表明,PD 有广泛的抗癌作用,且疗效满意。本文从增殖、凋亡、浸润和转移、免疫及抗炎等方面对PD抗肿瘤作用机制进行综述,为进一步更好开发和利用PD、发挥其抗肿瘤优势提供参考。
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