目的：研究新生儿缺氧缺血性脑病(HIE)临床分度与磁敏感加权成像(SWI)出血灶检出率的相关性。材料与方法选取30例经临床诊断为HIE的患儿进行SWI扫描，根据临床分度分别统计轻、中、重度患儿中SWI检出颅内出血灶的患儿例数，针对三种临床分度患儿的颅内出血灶检出率进行χ2检验及χ2分割法两两比较。结果三种临床分度患儿的颅内出血灶检出率具有统计学差异(χ2=12.438，P=0.02)；轻度HIE患儿出血灶检出率分别低于中度HIE患儿(χ2=5.690，P=0.017)和重度HIE患儿(χ2=9.545，P=0.002)，中度和重度HIE患儿出血灶检出率无统计学差异(χ2=1.173，P=0.279)。结论：轻度HIE患儿的SWI出血灶检出率明显低于中度和重度，通过SWI有无发现出血灶可以有效判断HIE患儿病情轻重。%Objective: To study the relationship between clinical grading and detection rate of hemorrhage by susceptibility weighted imaging (SWI) for newborns with hypoxic-ischemic encephalopathy (HIE). Materials and Methods: 30 cases of newborns with HIE diagnosed by clinical criteria were selected to receive SWI sequence scan. These newborns were divided into 3 groups according to clinical grading (mild, moderate, severe) and numbers of newborns in which intracranial hemorrhage detected by SWI were counted.χ2 test and partitions ofχ2 method were performed to compare the detection rate of hemorrhage by SWI according to clinical grading. Results:There had statistical difference for the detection rate of hemorrhage by SWI among three groups (χ2=12.438, P=0.02). The detection rate of hemorrhage by SWI for mild newborns with HIE was signiifcant lower than that of moderate newborns with HIE (χ2=5.690, P=0.017) and that of severe newborns with HIE (χ2 =9.545, P=0.002). There had no statistical difference for the detection rate of hemorrhage by SWI between moderate and severe newborns with HIE (χ2=1.173, P=0.279). Conclusions:SWI has higher sensitivity than conventional MRI sequence in detecting intracranial hemorrhage. The detection rate of hemorrhage by SWI for mild newborns with HIE is lower than that of moderate and severe newborns. We can infer the severity in newborns with HIE according to whether hemorrhage was detected by SWI.
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