目的 观察斑点追踪成像(STI)技术评价冠状动脉心脏病患者冠状动脉狭窄严重程度的价值.方法 对74例拟诊冠状动脉心脏病患者[冠状动脉狭窄组(n=59)和冠状动脉无狭窄组(n=15)]行常规超声和STI技术检查.根据冠状动脉Gensini评分将冠状动脉狭窄组分为轻、中、重度狭窄3个亚组.测量左心室整体平均纵向应变(GLS-Avg)、基底段平均纵向应变(GLS-Bas)、中间段平均纵向应变(GLS-Mid)及心尖段平均纵向应变(GLS-AP),比较两组间及3个亚组间的差异.结果 冠状动脉狭窄组GLS-Avg、GLS-Bas、GLS-Mid及GLS-AP均低于冠状动脉无狭窄组(P均＜0.001).冠状动脉狭窄组中,随着冠状动脉狭窄程度增加,GLS-Avg、GLS-Bas、GIS-Mid、GLS-AP降低,轻、中、重度狭窄亚组间两两比较差异均有统计学意义(P均＜0.05).冠状动脉狭窄组GLS-Avg、GLS-Bas、GLS-Mid及GLS-AP与Gensini评分均呈正相关(r=0.861、0.847、0.819、0.778,P均＜0.05).结论 采用STI技术获得的左心室整体纵向应变值可在一定程度上反映冠状动脉心脏病患者冠状动脉狭窄程度.%Objective To observe the value of speckle-tracking imaging (STI) in evaluation on degree of coronary artery stenosis in patients with coronary artery disease (CAD).Methods Totally 74 CAD patients,including 59 with coronary artery stenosis (coronary artery stenosis group) and 15 without coronary artery stenosis (no coronary artery stenosis group) underwent STI and echocardiography.Based on Gensini scores,the patients in coronary artery stenosis group were further divided into mild,moderate and severe subgroups.The average global longitudinal strain (GLS-Avg),basement global longitudinal strain (GLS-Bas),middle global longitudinal strain (GLS-Mid) and apical global longitudinal strain (GLS-AP) value were measured and compared.Results GLS-Avg,GLS-Bas,GLS-Mid and GLS-AP value in coronary artery stenosis group were lower than those in no coronary artery stenosis group (all P ＜ 0.001).In coronary artery stenosis group,with the increase of stenosis severity,GLS-Avg,GLS-Bas,GLS-Mid and GLS-AP value decreased,and statistical differences were found between each two subgroups (all P＜0.05).In coronary artery stenosis group,there were positive correlations between GLS-Avg,GLS-Bas,GLS-Mid,GLS-AP value and Gensini scores (r=0.861,0.847,0.819 and 0.778,all P＜ 0.05).Conclusion GLS value of STI can reflect the severity of coronary artery stenosis in CAD patients.
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