一体化PET/MR技术具有一次扫描可同时获得PET和MRI图像的独特优势,目前已逐步应用于临床.准确定量分析脑血流量(CBF)对研究脑血管病、脑肿瘤、癫痫等脑部重大疾病的发病机制及临床转归具有重要价值.一体化PET/MR可实现无创、简便、准确获得动脉输入函数,从而精准定量CBF.本文对一体化PET/MR评估CBF的研究进展进行综述.%The hybrid PET/MR has a unique advantage of simultaneous scanning of both PET and MRI images,which has been gradually applied in clinical practice.In the clinical studies of severe brain diseases (such as cerebrovascular disease,brain tumor and epilepsy),accurate quantification of cerebral blood flow (CBF) can help to understand the etiology,pathogenesis,and to make early diagnosis as well as therapeutic solutions.The hybrid PET/MR can implement a noninvasive,convenient and accurate method of arterial input function for quantification of CBF.The application of the hybrid PET/MR in quantification of cerebral blood flow were reviewed in this article.
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