Objective To explore the calcification and histopathological features of infiltrating ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS) by mammography. Methods Referring to the standard of BIRADS and the 2003 WHO a-bout breast cancer, the mammographic findings of surgically and pathologically confirmed 74 IDC and 68 DCIS whose mammography imaging only appeared as calcification were analyzed retrospectively. Results The shape and distribution of calcification in IDC and DCIS were statistically different (both P<0. 05) , among them the pleomorphic calcification and linear-branching calcification, the regional calcification and clustered, segmental calcification were significantly different (all F< 0. 008). Among 74 IDC, 35 complicated with DCIS, and the location of different pathological grading DCIS were statistically different (χ2 = 14. 353, P<0. 05). DCIS located peripherally of IDC liked to be low grade, while located in the central of IDC liked to be high grade. Conclusion IDC and DCIS are different from each other a lot in the shape and distribution of calcification. Comprehensive and careful analysis of imaging features of mammography is of great value to improve the diagnostic rate of early breast cancer.%目的 探讨乳腺X线检查中表现为单纯性钙化的浸润性导管癌(IDC)与导管原位癌(DCIS)的钙化特点及组织病理学特征.方法 参照BIRADS标准及2003年WHO关于乳腺癌的分类、分级标准,回顾性分析乳腺X线检查中表现为单纯性钙化、并经手术病理证实的74例IDC及68例DCIS患者的乳腺X线表现.结果 乳腺X线片中IDC与DCIS的钙化形态及分布差异均有统计学意义(P均＜0.05),其中多形不均质与线样分支状钙化,区域性钙化、成簇分布与节段性分布钙化在二者中差异均存在统计学意义(P均＜0.008).74例IDC中,35例合并DCIS,其中不同病理分级的DCIS所处位置不同,IDC病灶外周的DCIS多级别较低,中央的DCIS多级别较高(x2=14.353,P＜0.05).结论 DCIS与IDC部分钙化的形态、分布存在显著差异；乳腺X线检查中全面、仔细分析其影像特征,对提高乳腺癌早期诊断率有很大价值.
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