Objective To assess the correlations of cingulate gyrus volume with corrected factor, in order to provide standard volumetric method for cingulate gyrus.Methods Totally 627 Chinese healthy volunteers (aged from 18 to 60) underwent hrain three-dimensional MR scan. Cingulate gyrus volumes were manually measured with ROI using 3D volume analysis software, and were corrected by total intracranial volume (TIV) and whole brain volume (WBV), respectively. Correlation of uncorrected and corrected cingulate gyrusvolumes with TIV and WBV were analyzed, respectively. Results Uncorrected and corrected cingulate gyrus volume by TIV and WBV was (21. 01 + 2. 31)ml, (21. 11±2. 57)ml, (21. 06 + 2. 34)ml respectively for male, (19. 72 + 2. 31)ml, (19. 79 + 2. 28)ml, (19. 74 + 2. 04)ml respectively for female, (9.71 + 1. 54)ml, (9. 77 + 1.61)ml, (9. 75± 1. 54)ml respectively for left side, (10. 64 + 1. 58)ml, (10. 69 + 1. 53)ml, (10.67 + 1. 45)ml respectively for right side. Uncorrected cingulate gyrus volumes had lower correlation with TIV (male, female: r = 0.225, 0.385; left, right: r=0. 229, 0.366; all P<0. 05) , and higher correlation with WBV (male, female: r=0. 329, 0.473; left, right: r=0. 381, 0.419; all P<0. 05). Corrected cingulate gyrus volumes were correlated with TIV (male, female: r= - 0.378, -0.379; left, right: r= -0.368, -0.300; all P<0.05), and had lower correlation with WBV (male, female: r= - 0.297, -0.156; left, right: r= - 0.285, -0.197; all P<0. 05). Conclusion There is correlation between cingulate gyrus volume and TIV or WBV. Cingulate gyrus volume corrected with WBV is better.%目的 比较扣带回体积与校正因素的关系,为扣带回结构提供标准化的测量方法.方法 对627名18～60岁中国正常成年志愿者行全脑MR容积扫描,应用3D体积分析软件手工勾绘ROI,测量扣带回的体积,并分别以颅内容积(TIV)和脑体积(WBV)进行校正.对校正前、后的扣带回体积分别与TIV和WBV进行相关性分析.结果 校正前和TIV、WBV校正后的扣带回体积:男性分别为(21.01±2.31)ml、(21.11±2.57)ml、(21.06±2.34)ml,女性分别为(19.72±2.31)ml、(19.79±2.28)ml、(19.74±2.04)ml;左侧分别为(9.71±1.54)ml、(9.77±1.61)ml、(9.75±1.54)ml,右侧分别为(10.64±1.58)ml、(10.69±1.53)ml、(10.67±1.45) ml.校正前的扣带回体积与TIV的相关性不强(男、女:r=0.225、0.385；左、右侧:r=0.229、0.366;P均＜0.05),与WBV的相关性略高(男、女:r=0.329、0.473；左、右侧:r=0.381、0.419；P均＜0.05)；校正后的扣带回体积与TIV仍有相关性(男、女:r=-0.378、-0.379；左、右侧:r=-0.368、-0.300；P均＜0.05),与WBV相关性降低(男、女:r=-0.297、-0.156；左、右侧:r=-0.285、-0.197；P均＜0.05).结论 扣带回体积与TIV和WBV均有一定相关性；WBV校正效果优于TIV.
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