目的 应用ROC曲线分析方法评价320排动态容积CT冠状动脉成像(CCTA)诊断冠心病(CHD)的价值.方法 回顾性分析临床疑似冠心病的37例患者的CCTA和冠状动脉造影(CAG)资料,以冠状动脉狭窄≥50％作为冠心病诊断标准,对结果采用配对t检验及ROC曲线分析.结果 CCTA诊断冠心病的敏感度为78.57％ (55/70),特异度为95.13％(391/411),阳性预测值为73.33％(55/75),阴性预测值为96.31％(391/406),准确率为92.72％(446/481);CCTA和CAG结果呈高度相关性；CCTA的ROC曲线下面积为0.962. CCTA诊断的斑块数量较CAG多(68 vs 45).结论 320排动态容积CCTA诊断冠状动脉狭窄具有较高的准确性,能有效识别斑块及其危险程度.%To assess the value of 320-slice dynamic volume coronary CT angiography (CCTA) in the diagnosis of coronary heart disease (CHD) with ROC curve analysis. Methods Data of CCTA and coronary angiography (CAG) in 37 patients with suspected CHD were evaluated by using paired-samples t test and ROC curve analysis. Stenosis more than or equal to 50% of coronary artery was taken as the diagnostic standards of CHD. Results Compared with CAG, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of CCTA in diagnosing CHD was 78.57% (55/70), 95.13% (391/411), 73.33% (55/75), 96,31% (391/406) and 92.72% (446/481), respectively. There was no significant difference between CCTA and CAG. The area under curve of ROC of CCTA was 0. 962. The plaques detected by CCTA (68) were more than CAG (45). Conclusion 320-slice dynamic volume CCTA has good capabilities to identify different kinds of plaques and diagnose on narrow degree of coronary artery.
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