Objective To investigate the value of parametric imaging of CEUS in diagnosis of portal venous system thrombosis using dynamic vascular patterns (DVP).Methods Forty-one patients with portal venous system thrombosis (PVT), who were potential candidates for liver transplantation, underwent CEUS.Sonoliver CAP software was used to analyze the CEUS images and reconstruct DVP parametric images.Results Portal vein tumor thrombi (PVTT) enhanced rapidly in arterial phase and filling defect in the portal phase and late phase.The rise time (RT), time to peak (TTP) and mean transit time (mTT) in portal vein tumor thrombosis were fast than that in the surrounding liver parenchyma (all P＜0.01).The maximum intensity (Ⅰmax) in PVTT was larger than that of surrounding liver parenchyma (P=0.001).Portal vein blood thrombosis did not enhance in all phase.Conclusion Parametric imaging of CEUS could demonstrate the difference of flow perfusion static between PVTT, PVBT and surrounding liver parenchyma dynamically and directly, therefore being helpful to differential diagnosis of benign from malignant lesions.%目的 探讨CEUS参数成像在诊断及鉴别诊断肝移植术前门脉系统栓子中的临床应用价值.方法 回顾性分析接受CEUS检查并经临床或病理证实的41例肝移植术前门脉系统栓子患者,观察造影剂灌注模式,并利用sonoliverCAP定量分析,以门静脉栓子与周围肝实质的增强水平差值为参数进行动态血管模型(DVP)参数成像构建.结果 门静脉瘤栓动脉期呈快速增强,门脉期及延迟期明显消退.门静脉瘤栓的上升时间、达峰时间、平均渡越时间分别快于周围肝实质,差异均有统计学意义(P均<0.01);门静脉瘤栓的峰值强度高于周围肝实质,差异有统计学意义(P=0.001).门静脉血栓三期均无造影剂灌注,各参数值均为0.结论 CEUS参数成像能直观反映门脉系统栓子与周围肝实质问灌注差异,鉴别栓子性质.
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