目的 探讨3.0T MR DTI及脊髓扩散张量纤维束示踪成像(DTT)技术的可行性及临床应用价值.方法 应用3.0T MR成像系统对49名健康志愿者行脊髓DTI.分别测量颈髓、下段胸髓的ADC和FA值,同时进行各段脊髓DTT研究.采用单因素方差分析进行统计学分析.结果 在颈髓与下段胸髓之间ADC和FA值差异均无统计学意义(P=0.745、0.196).在DTT彩色编码图上,正常脊髓纤维束显示为头尾向的一束,存在头尾侧各向异性.结论 脊髓DTI是描述扩散特征并直观显示脊髓纤维束的有效检查技术,可为脊髓病变提供扩散定量值参考.%Objective To observe the feasibility and clinical values of DTI and tractography (DTT) of spinal cord. Methods Spinal cord DTI of 49 normal subjects were obtained on a 3. OT MR scanner. ADC and FA values were measured on the cervical and lower thoracic cord. The tracts were visualized. One way ANOVA was used to test the differences among spinal segments. Results There was no statistical difference among segments of cervical and lower thoracic cord (P = 0. 745, 0. 196). On DTT maps, the normal spinal cord was depicted as a fiber tract showing color-encoded cephalocaudal-ly. Conclusion DTI is a robust method for demonstrating the fiber tracts of the spinal cord and its diffusion characteristics, which can provided references of diffusion values for the spinal cord conditions.
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