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首页> 中文期刊> 《中国医学影像学杂志》 >磁共振功能成像在鉴别脑胶质瘤术后复发与放射性损伤中的应用

磁共振功能成像在鉴别脑胶质瘤术后复发与放射性损伤中的应用

         
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Purpose To investigate the clinical application and manifestation of perfusion weighted image (PWI), diffusion weighted image (DWI) and 1H-magnetic resonance spectroscopic image (1H-MRS) in differentiating postoperative recurrent glioma and radiation injury. Materials and Methods The images and clinical data of 12 cases with postoperative recurrent glioma and 13 cases with radiation injury were retrospectively analyzed. Results The maximum and average CBVnorm of recurrent glioma were 3.34±0.54 and 4.00±0.61, respectively. The maximum and average CBVnorm of rradiation injury were 1.18±0.32 and 1.35±0.35, respectively. There was a statistical difference between them (P<0.01). ADC value of recurrent glioma and radiation injury were 1.49±0.28 and 1.62±0.26, respectively, which showed no significant difference (P>0.05). Cho/Cr and Cho/NAA value of recurrent glioma were 2.72±1.18 and 2.32±0.83, respectively, and those of radiation injury area were 2.09±1.41 and 1.68±0.74, respectively. There was no significant difference between them (P>0.05). Conclusion PWI is better than DWI and 1H-MRS in differentiating postoperative recurrent glioma from radiation injury. DWI and 1H-MRS can be used as assistant methods.%　　目的探讨磁共振灌注成像（PWI）、扩散加权成像（DWI）和1H-磁共振波谱成像（1H-MRS）在鉴别脑胶质瘤术后复发与放射性损伤中的临床应用价值。资料与方法回顾性分析12例脑胶质瘤复发和13例脑胶质瘤放射性损伤患者的PWI、DWI和1H-MRS影像资料和临床资料。结果脑胶质瘤复发区平均标准化脑血容量（CBVnorm）（3.34±0.54）与放射性损伤区（1.18±0.32）比较，差异有统计学意义（P<0.01）。脑胶质瘤复发区最大CBVnorm（4.00±0.61）与放射性损伤区（1.35±0.35）比较，差异有统计学意义（P<0.01）。脑胶质瘤复发和放射性损伤区标准化ADC值分别为1.49±0.28和1.62±0.26，差异无统计学意义（P>0.05）。脑胶质瘤复发区Cho/Cr和Cho/NAA值分别为2.72±1.18和2.32±0.83，放射性损伤区Cho/Cr和Cho/NAA值分别为2.09±1.41和1.68±0.74，差异均无统计学意义（P>0.05）。结论PWI在脑胶质瘤复发与放射性损伤的鉴别诊断中具有更高的价值， DWI和1H-MRS仅能起到辅助作用。

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