To report one case of cryptococcal meningitis misdiagnosed as tuberculous meningitis.The patient was a 49-year-old female with intermittent headache,low fever,progressive visual and hearing damage for more than three months,who was diagnosed as tuberculous meningitis.After anti-tuberculous treatment for more than a month,the patient developed an elevated temperature to 39.4 degree,a severe headache and vomiting for 3 days.And the fungus cultivation of eerebrospinal fluid gotten by lumbar puncture was positive.Beside,the cryptococcal antigens titer testing was 1 ∶ 80.So the patient was diagnosed as cryptococcal meningitis.Nowdays the condition of the patient was better than before and the etiological examinations of the cerebrospinal fluid become negative after antifungal treatments for half a year.%报道误诊为结核性脑膜炎的隐球菌脑膜炎1例.患者女性,49岁,间歇性头痛、低热,伴视力、听力进行性下降3个月余,诊断为结核性脑膜炎,行抗结核治疗1个月余.3d前患者体温骤升至39.4℃C,伴剧烈头痛,呕吐.脑脊液真菌培养为隐球菌,脑脊液隐球菌抗原滴度1∶80.诊断:隐球菌脑膜炎.经抗真菌治疗半年后,患者一般情况好转,脑脊液病原学结果阴性.
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