Obesity is not only a metabolic problem, but also a chronic inflammatory disease. Adipose tissue plays a major role in the obesity-induced insulin-resistant state. This review will focus on the roles of macrophages, T lymphocytes, and mast cells in the inflammatory response.%肥胖是一种代谢性疾病,同时也是一种慢性炎症状态.脂肪组织是炎症反应的始动环节,其中巨噬细胞发挥着促炎的重要功能,可以引起胰岛素抵抗.另外T细胞和肥大细胞也参与了脂肪组织的慢性炎症过程.
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