首页> 中文期刊> 《中国骨质疏松杂志》 >呼和浩特地区人群中应用FRAX骨折风险预测工具进行骨折风险评估的临床研究

呼和浩特地区人群中应用FRAX骨折风险预测工具进行骨折风险评估的临床研究

         

摘要

目的 探讨FRAX骨折风险预测工具评价呼和浩特蒙古族与汉族人群的骨折风险性的临床应用性.方法 选取2016年1月至2016年6月在我院检查者435例(蒙古族56例,汉族379例),收集FRAX风险评估工具所需各项危险因素,输入FRAX中国版,计算10年内主要部位(包括髋部、脊柱、肱骨近端及腕部)及髋部骨折的概率,比较不同民族FRAX预测值.结果 354例女性研究对象中,蒙古族女性未来10年主要部位骨折概率1.1% ~20.5%,髋部骨折概率0%~13%,汉族女性未来10年主要部位骨折概率1.1%~28.8%,髋部骨折概率0% ~ 27%.81例男性研究对象中,蒙古族男性未来10年主要部位骨折概率1.2% ~7.3%,髋部骨折概率0% ~4%,汉族男性未来10年主要部位骨折概率1.1% ~17.7%,髋部骨折概率0%~6.8%.蒙古族与汉族主要部位骨折及髋部骨折概率之间比较无明显差异(P>0.05),然而蒙古族人群股骨颈及腰椎骨密度显著高于汉族人群(P<0.05).结论 呼和浩特地区蒙古族人群未来10年髋部骨折与主要部位骨折风险性与汉族人群未表现出明显差异.%Objective To evaluate the applicability of FRAX in the population of Hohhot,Inner Mongolia.Methods A total of 435 subjects (56 Mongolian and 379 Han) with osteoporotic fractures,who were examined in our hospital from Jan to June 2016,were selected.The clinical data of all the patients were retrospectively analyzed.All the risk factors contained in FRAX prediction tool were collected.Data including BMD of femoral neck were input into the FRAX prediction tool.Then,the probability for major fractures (hip,spine,humerus and wrist) and hip fracture in the next 10 years was calculated,and comparisons between the two ethnic groups were made.Results In the 354 female subjects,in the Mongolian ethnic group the probability of major fracture and hip fracture in the next 10 years was 1.1%-20.5% and 0%-13%,respectively,and for Han,the probability of major fracture and hip fracture was 1.1%-28.8%,and 0%-27%,respectively.In the 81 male subjects,for the Mongolian ethnic group the fracture probability of major fracture and hip fracture in the next 10 years was 1.2%-7.3% and 0%-4%,respectively,and for Han,the probability of major fracture and hip fracture was 1.1%-17.7%,and 0%-6.8%,respectively.The difference in fracture probability for major and hip fractures between Mongolian and Han was not significant (P > 0.05).However,femoral neck and lumbar spine bone mineral density of Mongolian subjects were significantly higher than that of Han subjects (P < 0.05).Conclusion There were no significant differences between the Mongolian and Han population in Hohhot for the fracture probability of major and hip fractures.

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