coherence tomography (OCT) is a real-time and non-invasive technique which can acquire high-resolution,cross-sectional images of tissue in vivo.An image produced by OCT resembles the tissue architecture observed in histology and can therefore be considered as an "optical biopsy".As an imaging diagnostic test,OCT has been widely used in ophthalmology to image the retina and in cardio vascular applications to visualize vulnerable plaque in the coronary vasculature,as well as in urology and gastroenterology for mucosa epithelium imaging.Because the potential for OCT to discern the layered microstructure of vocal folds,OCT imaging is becoming an increasingly important technology for voice science,including detection of vocal folds structure,differential diagnosis of benign and malignant tumors,phonomicro surgery,observation of vocal folds vibration.%相干光断层扫描技术(optical coherence tomography,OCT),又称为光学相关断层扫描技术,是近年发展起来的非接触式、无损、实时、高分辨率的影像诊疗技术,首先主要应用于眼科视网膜沟的检测,以及心血管疾病中对于冠状动脉内膜不稳定粥样斑块的探查.同时还应用于泌尿外科及消化内科对于黏膜上皮疾病的诊断.由于OCT能够准确检测声带的分层结构,目前逐渐成为嗓音医学中十分重要的临床检查手段之一,应用于声带结构的检测,良恶性疾病的鉴别诊断,嗓音显微外科手术以及对声带振动形态的观察等方面.
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