Objective To explore the characteristics and significance of cartilage invasion in transglottic carcinoma.Methods Fifty cases of transglottic carcinoma were chosen and the collodin-embedded specimens of the whole-organ serial section were observed.(1)The invasion rate of the cartilage in tansglottic carcinoma was 64% (32/50); the invasion rate of the thyroid and that of the thyroid and cricoid were 34% (17/50) and 30%(15/50) respectively; (2)the cartilage was invaded in the early stage;(3)the metastatic rate of the cervical lymph node? was 44%(22/50) in transglottic carcinoma; it was 56.25%(18/32) in cartilage invaded cases, and 22.22%(4/18) in non-cartilage invaded cases; there was remarkable difference(P<0.05).Conclusion Sufficient recognition of cartilage invasion is important in the diagnosis and treatment of transglottic carcinoma.%目的探讨跨声门癌喉软骨支架受累的特点及意义。方法选择临床喉全切除标本50例，火棉胶包埋，连续切片观察。结果跨声门癌喉软骨支架受累为64%(32/50)，其中单纯甲状软骨受累为34%(17/50)，甲状软骨和环状软骨同时受累为30%(15/50)；肿瘤早期就可浸润喉软骨支架；跨声门癌颈淋巴结转移率为44%(22/50)，侵及与未侵及喉软骨支架者转移率分别为56.25%(18/32)、22.22%(4/18)，二者差异显著(χ2=4.12，P<0.05)。结论充分认识跨声门癌喉软骨支架受累对临床诊断治疗具有重要指导意义。
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