目的 探讨自动功能成像(AFI)技术评价先天性甲状腺功能低下症(CH)患儿左室局部收缩功能的临床价值.方法 应用AFI技术对35例甲低患儿(CH组)及30名年龄匹配的正常儿童(对照组)左室室壁各节段纵向运动进行检测,实时获取左室收缩纵向峰值应变(LPSS)及其心室各节段分析图(牛眼图).结果 与对照组比较,CH患儿左室前壁基底段,侧壁心尖段、室间隔基底段、中间段,后壁收缩纵向峰值应变明显减低(P＜0.05).两组间左室收缩功能常规参数比较差异无统计学意义(P＞0.05).结论 应用AFI技术可早期发现CH患儿局部收缩功能改变,为临床治疗提供可靠依据.%Objective To study the value of automated function imaging (AFI) technology in the evaluation of regional left ventricular systolic function of children with congenital hypothyroidism (CH). Methods AFI technology was applied to 35 cases of congenital hypothyroidism (CH group) and 30 age-maiched normal children (control group) for left ventricular wall segments and longitudinal motion detection, and real-time left ventricular systolic longitudinal peak strain (LPSS) and left ventricular segmental analysis diagram were obtained. Results Compared to control group, anterior basal segment, the side wall of the apical segment, septal basal section, middle section and. the posterior wall of the longitudinal peak systolic strain in CH group were significantly decreased(P< 0.05). The conventional parameters of left ventricular systolic function had no significant differences in the two groups(P>0.05). Conclusion Early changes in the regional cardiac systolic function can be found by AFI technology in children with CH.AFI technology can provide a reliable basis for clinical treatment.
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