Objectives To discuss the treatment effect and affecting factors of Tuberculosis of DOTS strategy. Methods Cox model was applied to analyze the recovery rate of 1 502 cases of tuberculosis patients at Bao'an dis trict of Shenzhen City in 2008. Results The median survival time was 194 days. Log-Rank test results showed that the course of TB had statistically differences between two sex patients, initial treatment and re-treatment patients, symptomatic and asymptomatic patients, the different mode of tuberculosis-case-finding patients, the different re sult of first visit patients. Cox model multivariate analysis result showed that the sputum examination result of first visit. The history of chemotherapy and the sex were the independent factors which influences the course of TB. Posi tive sputum examination of first visit results, re-treatment and female were the hazards. The RR was 15. 05, 6. 34, 1. 17 respectively. Conclusions The smear-positive patients, re-treatment patients and female TB patients should be focused on shortening the duration and improving the curative effect of TB.%目的 探讨DOTS策略下结核病的治疗效果和影响因素.方法 以深圳市宝安区2008年1 502例结核病随访登记管理病人为研究对象,采用非参数的Cox比例风险同归模型对结核病的治愈率进行单因素和多因素回顾性分析.结果 深圳市宝安区2008年结核病的中位生存期(即结核病中位治愈天数)平均为194天,Log-rank单因素检验显示:不同性别、化疗史、就诊时有无症状、发现方式和初诊查痰结果的患者结核病病程有统计学差异(P＜0.05)；Cox回归模型多因素分析显示,初诊查痰结果、化疗史和性别是影响结核病病程的独立因素；初诊痰菌阳性、复治和女性是影响结核病病程的危险因素,相对危险度分别为15.05,6.34,1.17.结论DOTS策略实施过程中要缩短结核病病程和改善治疗效果,应重点关注涂阳、复治和女性结核病人.
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